Wednesday, 23 November 2016

Bone marrow transplant for Thalassemia

Bone marrow transplant for thalasemia major.
Transplanting bone marrow is as simple as blood donation,now days
The blood forming stem cells in the spongy tissue of the donor's marrow are extracted through a peripheral blood stem cell(PBSC) process.
The donor is first injected with a drug called Fligrastim , which helps in producing more stem cells in the donor's body.
Blood is then removed from one arm , and passed through a disposable installed in a machine that separates the stem cells, while the remaining blood compnents are passed through the other arm.
So technically, the stem cells that are collected are the excess ones, generated with the drug's help , and donor loses nothing.
Transplanting bone marrow used to be a complex , painful surgical procedure in which the spongy tissue was taken from the pelvic bone , but that was years ago . Medical science had now simplified it to some thing as trouble free a donating your blood and not a prick more. And as awareness grows , this is encouraging more people to come forward and help revive patient's of blood cancer( like leukaemia) and blood disorders( like Thalassemia major)
Bone marrow is the flexible tissue inside the bones where blood forming stem cells are born , and can be harvested.In patients suffering from blood diseases, these cells stop making healthy blood.The cure is to replace them with functional stem cells from a donor . The tricky part is to find a perfect match.
For a transplant, the donor and the recipient should have the same type of HLAs or human leukocyte antigens , the odds of which are 1 in 20,000 .
A person registered to donate is first tested for any existing diseases. Then a mouth swab is collected for HLS tests. Ten of the donor's antigrns need to agree with the recipient's corresponding antigens, something referred to as a 10/10 match in medicalese. Initially,through , MDRI tests six antigens,further tests are done if these match up .
The donor's from MDRI helped have lived of five critically ill patients, whose only shot at staying alive was bone marrow from a person who is perfect match .
Kindly donate your blood for this noble cause.

1 comment:

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