Relationships of Remedies

Every drug in almost all our textbooks on Materia Medica has a paragraph devoted to it detailing Its relationship with other drugs. Some drugs are mentioned as antidotes others as complementary or inimical. Clarke in his Clinical Repertory has tabulated these related drugs and has added other columns like follows well, followed well by and also natural relationship to these tables.
It would be interesting and instructive to see how these lists have been prepared and to investigate the basis for regarding a certain remedy as antidotal or complementary to a certain other remedy ? Several questions also arise in regards to this matter. After administering a particular medicine, when a change of prescription becomes necessary, should we necessarily refer to these lists and then only select the appropriate drug that is supposed to follow it well ? Should we invariably avoid the medicine listed as antidotal or beware against giving those listed as the inimical ones ? Unless we ascertain and comprehend the basis for arriving at these lists but we shall have to be satisfied with the existing ones prepared so carefully more than hundred years ago, making a mechanical selection from these lists wich may encourage a tendency to routines. The several blank columns of Clarke's Tables of Relationship have yet to be filled in. The numerous drugs introduced by or in common use in other systems of medicine require to come into these lists,so that we may know at least their appropriate antidotes for us to use as wall breakers , when patients under these systems come to the Homoeopaths for treatment.
We shall first define a few terms used in denoting relationships.
1 Antidote , is defined in Oxford Dictionary as a medicine given to counteract a poison or a disease.In our literature we use antidotes to counteract, minimize  or moderate the over action or undesired effects of a drug either during a proving or during its therapeutic use.
2 Complement, that which continues or completes the work of the medicine already given.
3  Compatible, able to co exist, that which can be used along with.
Naturally we expect that a complementary medicine will be also compatible.
4 Incompatible or inimical, is a medicine which will harm the patient or increase his sufferings, or spoil the case, if used immediately before or after the medicine under consideration.